BI-MODAL
Overview
Why are you doing this study?
We want to understand how people feel and how they make decisions. We know mood instability has been associated with
difficulties in decision-making and emotional processing. By studying the brain and behavior of people with and without it,
we aim to better understand the processes that contribute to the disruption seen in this disorder.
What does the study involve?
- Completing several brief questionnaires
- Playing some computer games
- Downloading and using our smartphone app
The study will last for 8 weeks. If you complete the study you will receive up to £65 in total.
Why me?
We are looking for volunteers aged 16-45 and who speak and understand English.
Are you interested in taking part in this study?
Planned end date
31 Jan 2025 20:07Conditions
Bipolar DisorderInclusion Criteria
Inclusion criteria for patients with mood instability:
1. Aged 16-45.
2. Male or female.
3. History of mood instability or received a Bipolar Disorder diagnosis (according to the Diagnostic and Statistical Manual of Mental Disorders- 5; DSM-5).
4. Not in a mood episode for least 4 weeks prior to enrolment in the study.
5. Fluent in English.
6. Willing and able to provide written informed consent.
Inclusion criteria for healthy controls:
1. Aged 16-45.
2. Male or female.
3. Fluent in English.
4. Willing and able to provide written informed consent.
Exclusion Criteria
Exclusion criteria for patients with mood instability :
1. History of a neurological disorder.
2. Developmental disorders including learning disability.
3. Substance dependence in the past 6 months (excluding tobacco) as determined by self-report and/or diagnostic interview.
4. Recreational drug use within 7 days of enrolment in the study.
5. Participation in a Clinical Trial of an Investigational Medicinal Product within 1 month of enrolment in the study.
6. Changes to psychiatric medication, or received antipsychotic medication, for > = 6 weeks.
Exclusion criteria for healthy controls:
1. Diagnosis of Axis I psychiatric disorder.
2. Neurological disorders history.
3.Developmental disorders including learning disability.
4. Substance dependence in the past 6 months (excluding tobacco) as determined by self-report and/or diagnostic interview.
5. Recreational drug use within 7 days of enrolment in the study.
6. Participation in a Clinical Trial of an Investigational Medicinal Product within 1 month before enrolment in the study.
Exclusion criteria for all participants taking part in MRI scan:
1. Presence of any magnetic metal device that cannot be removed (i.e. pacemaker, cochlear implant, etc).
2. Pregnancy or suspected pregnancy.
