Back to the list

Using belief-updating and speech to predict psychosis relapse

Overview

About the study:

Given the impact that experiencing symptoms of psychosis has on a person's life, identifying patients who might and might not relapse after a period of recovery, is really important for successful ongoing treatment. Evidence suggests that belief-updating (in other words, learning and the processing of information), and patterns in speech might be promising markers to predict future potential relapse. 

The primary purpose of this study is to use online belief-updating and speech tasks to investigate the relationship between these two potential markers and future outcomes for patients.

What will it involve? 

This study will involve online tasks and clinical interview which can be done either online (via Microsoft teams) or in-person depending on your preferences. The study includes 3 visits over 1-year period.

Visits:
•    Visit 1: online cognitive tasks, basic demographics, and clinical interview
•    Visit 2: 6 months after visit 1: clinical interview and online cognitive tasks
•    Visit 3: 1 year after visit 1: clinical interview and online cognitive tasks

Timing:
•    Tasks: 45-60 minutes in total. 
•    Clinical interviews: 2-3 hours with breaks in between

Who are we looking to recruit?

We are looking to recruit people who have experienced one episode of psychosis.

The main eligibility criteria:

Inclusion
•    You are 18 to 40 years old
•    You are able to communicate in English
•    You have access to laptop, computer or smartphone
•    You have a diagnosis of first episode psychosis

Exclusion
•    If you have experienced more than one previous episode of psychosis
•    If you have any other neurological disorders
•    If you have a visual or physical motor impairment that will make it hard for you to complete online cognitive tasks

Rewards and expenses:

You will be compensated separately after each component has been completed, if you complete the whole study (including baseline and two follow-up visits), you will receive £180 in total.

Are you interested in taking part in this study? 

Find out more by filling in this form

Planned end date

06 Jan 2027 00:00

Conditions

Hallucinations,Psychosis

Inclusion Criteria

Inclusion criteria (FEP)

Participants will be recruited from two routes:

  1. Participants who are part of Urban Mind study will be invited to the present study;
  2. Patients who are referred to the following early psychosis teams will also be invited to the study: Lambeth Early Psychosis (LEO), Southwark Team for Early Psychosis (STEP), Lewisham Early Intervention Service (LEIS), Croydon Outreach Assessment Support Team (COAST), Central and North West London NHS Foundation Trust (NWLFT).

Participants from both routes will need to meet the following criteria:

  • all participants are 18 to 40 years old
  • all participants have capacity to consent to take part in the study
  • all participants need access to laptop, computer or mobile to complete the tasks
  • all participants met FEP as defined by a DSM-IV diagnosis of schizophrenia, schizophreniform disorder, schizoaffective disorder, or delusional disorder based on the Structured Clinical Interview for DSM-IV (SCID-I) (First et al., 2002).

Inclusion criterion (healthy control)

  • All participants are 18 to 40 years old
  • All participants have capacity to consent to take part in the study
  • All participants have access to laptop, computer or mobile to complete the tasks

Exclusion Criteria

Exclusion criteria (FEP)

Experienced more than one previous episode of psychosis

  • Any other neurological disorders that could potentially interfere with study process or patients’ safety
  • Participants are unable to fully comprehend the purpose of the study or make a rational decision whether or not to participate
  • Any other clinically significant medical condition or circumstances that could affect patient safety, preclude evaluation of response, interfere with the ability to comply with study procedures, or prohibit completion of study
  • A visual or physical motor impairment that could interfere with study tasks 

Exclusion criterion (healthy control)

  • History of psychotic disorder
  • Any other clinically significant medical condition or circumstances that could affect patient safety, preclude evaluation of response, interfere with the ability to comply with study procedures, or prohibit completion of study
  • A visual or physical motor impairment that could interfere with study tasks
Global Banner